LYMEPOLICYWONK: The IDSA Guidelines And Embers At a Glance Table.

03 May
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I have blogged about the Embers study previously. The Embers study essentially dismantles much of the science that the IDSA relies on in their Lyme guidelines. This post presents a table of the IDSA guideline assumptions and recommendations that the Embers study refutes. This is just one of the many, many reasons the IDSA guidelines should be revised.
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LYMEPOLICYWONK: Was this important Lyme study hidden for 12 years?

22 Feb
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The recently published monkey study by Embers and colleagues regarding the persistence of Lyme after antibiotic treatment is important for two distinct reasons. The first is because of the scientific results of the study, explained in a 5-part article I posted on this blog last week. (Links follow this post.) The second, more troubling reason, is because publication of this important research was delayed for over a decade. And that delay has seriously harmed Lyme patients. Continue reading

LYMEPOLICYWONK: Embers Monkey Study Part 3. IDSA 28 Day Treatment Protocol Fails to Clear Infection.

15 Feb
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This is Part 3 of a series on the Embers study of Lyme disease in non-human primates. As described in Part 1 of the series, the Embers monkey research study posed three questions: one regarding treatment of early disseminated Lyme disease, one regarding treatment of late disseminated Lyme disease, and one regarding the ability of the C6 to accurately detect infection. This part focuses on the first question–the ability of 28 days of antibiotics to eradicate infection in early disseminated Lyme disease. The 28 day treatment with doxycycline was intended to test the treatment recommendation of the Infectious Diseases Society of America (IDSA). The Embers study found that infection persisted in all monkeys treated with this protocol. Continue reading

LYMEPOLICYWONK: Embers Monkey Trials Part 2: Chronic Lyme Disease Treatment and Persistence

14 Feb
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This is Part 2 of a series on the Embers study of Lyme disease in non-human primates. As described in Part 1 of the series, the Embers monkey research study posed three questions: one regarding treatment of early disseminated Lyme disease, one regarding treatment of late disseminated Lyme disease, and one regarding the ability of the C6 to accurately detect infection. This part of my blog series on the Embers study focuses on the second question–the ability of 90 days of antibiotics to eradicate infection in late disseminated Lyme disease. The researchers defined late disseminated Lyme disease as 27 weeks after inoculation. Rhesus macaques were chosen as the animal model because they experience many of the key signs of human Lyme disease, including neuroborreliosis ( an infection of the brain or nervous system.) Continue reading