Advanced Imaging Shows Lyme-Related Brain Fog is Real Cutting-edge imaging modalities can detect objective changes in the brains of Lyme disease patients

By Nancy Dougherty


John Hopkins Lyme disease research T here are approximately 476,000 people diagnosed with Lyme disease annually in the US. Of these, an estimated 10-20% suffer from impairing symptoms well beyond the acute phase of infection.

Persistent symptoms include severe fatigue, pain, and cognitive problems. Vexingly, these symptoms can be difficult to validate using current diagnostic tests.

Patients are often told by their health practitioners: “your tests are normal, it’s in your head” (aka psychosomatic).

Researchers have discovered, however, that by using more advanced imaging modalities, brain changes can be objectively detected in Lyme disease patients.

For example, clinical researchers at Johns Hopkins University School of Medicine have used novel PET imaging, functional MRI (fMRI), and diffusion tensor imaging (DTI) to identify inflammatory, functional, and structural abnormalities in the brains of Lyme disease patients as compared to healthy controls.

Their findings indicate that Lyme-disease-associated brain alterations are biologic and measurable, not psychosomatic. These discoveries are significant but not yet well known by the physician community or broadly available to clinicians.

What does “brain fog” mean?

Brain fog is a term used to describe difficulties with cognitive functions such as working memory, focusing, concentrating, planning, organizing, word recall, processing speed, and mental fatigue.

Johns Hopkins University School of Medicine’s findings indicate that Lyme-disease-associated brain alterations are biologic and measurable, not psychosomatic.

Working memory enables one to do tasks quickly or easily solve a problem without looking up information. This includes quickly learning a new computer program or using names or numbers for a routine task.

Mental fatigue is akin to how one feels after taking a long test that requires remembering detailed information or doing a complicated mental task when short on sleep……..Join or login below to continue reading.

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