Compared to patients with other chronic diseases, patients with CLD reported significantly lower health quality status, more bad mental and physical health days, and greater activity limitations…
Summary of evidence from animal models and human studies that support persistent spirochetal infection as the cause of chronic Lyme disease…
Patients with the persistent form of Lyme disease suffer profound disability equivalent to that of patients with congestive heart failure…
Any new Lyme vaccine will need extensive safety testing, more transparency about side-effects, and improved patient communication on the part of the vaccine manufacturer to allay valid patient concerns about safety….
Until we scrap the worthless commercial tests for Lyme disease and find a better way to make the diagnosis of this protean illness, the “Lyme wars” will continue unabated…
The medical basis for diagnostic and therapeutic uncertainty in Lyme disease, including variability in clinical presentation, shortcomings in laboratory testing procedures, and design defects in therapeutic trials…
A web-based survey conducted over nine months was analyzed for this study. The
survey focused on medical status, access to healthcare, and burden of illness for patients with Lyme disease…
We propose the need for an HIV/AIDS-style ‘‘Manhattan project’’ to combat this serious epidemic that threatens the physical and mental health of millions of people around the world…
The AIDS epidemic has taught us that a high index of suspicion, rational standardized testing methods and aggressive combination antimicrobial therapy can have a significant impact on infection control….
Gender bias in Lyme testing, and gender-specific immunopathology are important issues that are overlooked in the faulty Lyme guidelines authored by Wormser and Shapiro, which are currently under review…
The opportunity for the pharmaceutical industry to develop new drugs targeting novel infectious processes in a well-defined patient population will lead to broader recognition and more effective treatment of Lyme disease over the next decade….
A recent publication defined the “Axis of Evil” as physicians who treat patients with prolonged course of antibiotics, “special laboratories” that perform “inaccurate” Lyme testing and the Internet, which promotes “Lyme hysteria”…
In a recent settlement with IDSA, the Attorney General noted important commercial conflicts of interest and suppression of scientific evidence that had tainted the guidelines process. This publication explores two broad ethical themes that influenced the IDSA investigation…
When guidelines panels fail to safeguard the integrity of the guideline development process, the quality of guidelines may be eroded and fall short of the primary goal of guidelines – namely improving patient outcomes….
The guidelines address 3 clinical questions – the usefulness of antibiotic prophylaxis for known tick bites, the effectiveness of erythema migrans treatment and the role of antibiotic retreatment…
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